Which one? There is the one from Pandia Press called REAL Science Odyssey and then there is REAL Science 4 Kids. We just did the first chapter in the Chemistry book from Pandia.. and we really liked it. Right now we can't keep with it because the labs require some things we just don't have around the house, and I don't have any money to spare these days.. so we are going a different route, but I wish we weren't!
I used Real Science 4 Kids Prelevel Chemistry in a co-op last year and really enjoyed it. The kids liked the experiments and were able to understand the text. I'm going to use their level 1 Biology this year and can hardly wait to get started.
I use REAL Science from Odyessy from Pandia Press, we're doing the Earth and Space Science... I love it.. I love that it is hands on and lab based. I am going to add some supplemental things in for the weather unit that I think are needed but other then that we will be following it pretty closely. Next year I'm going to purchase the Life Science and then the Chemistry the year after. If you order the ebook from Pandia it's cheaper. Also Pandia has try before you buy and it is at least one unit of lessons to try. http://pandiapress.com/real_science.htm